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General Information

Oxycodone is a strong painkiller used to treat severe pains, belonging to a group of medicines called opioids. Doctors prescribe it for injuries, surgeries, or chronic conditions, such as cancer pain.

Oxycodone works by blocking pain signals in the brain. However, tablets, capsules, and liquids can cause drowsiness, nausea, and dizziness.

Taking too much can be dangerous and get you addicted. Never mix with alcohol or other drugs without a doctor’s advice. It is crucial always to take the correct dose to avoid side effects. It should be stored in a safe place, away from children.

If it is stopped suddenly, it can cause a feeling of sickness. Only take if prescribed. Misuse can be hazardous.

Administration

Oxycodone must be taken as directed by the doctor. Oxycodone is available in tablet, capsule, and oral solution forms. You should swallow the tablet whole, with a drink of water. Do not crush or chew.

You may take it with food or between meals; food will help to avoid nausea. The liquid form must be carefully measured with the dosing spoon. If pain persists, do not take extra doses; wait for your next dose.

Do not take other drugs while taking this medication. It is never safe to give the medicine to anyone else. Store the medicine out of the reach of children.

Do not stop taking medication suddenly, or the withdrawal symptoms may occur; decrease the amount slowly otherwise.

Mechanism

Oxycodone affects the brain’s perception and response to pain. It attaches to opioid receptors, which transmit signals that ameliorate pain and have a calming effect. This thereby lessens the sensation of the body towards pain.

Further, it slows the rate of breathing and makes one drowsy. With time, the brain can develop tolerance, leading to dependence on oxycodone. If taken in high quantities, it can cause serious problems like respiratory distress.

Effects typically appear between one-half to one hour after dosing and last up to several hours. Because it is acting on the brain, withdrawal symptoms can occur from abruptly stopping oxycodone.

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Dosage

The dosage must depend on the level of pain, the patient’s health status, and the doctor’s recommendation. The time interval is usually four to six hours as and when needed.

• Adults: 5–15 mg; ordinarily, 4–6 hours as needed.
• Extended-release tablets: 10 mg or more every 12 hours for the treatment of severe pain.
• Children: Should only be given under strict medical supervision.
• Patients with asthma, elderly, or weak: Start with a lower dose to avoid risks.
• Condition of overdose: Overdoses can lead to respiratory slowdowns, and overwhelm may even be fatal.

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Side Effects

Oxycodone does help relieve pain, but it may cause several side effects. These may be mild or serious. Generally, these are drowsiness, dizziness, and nausea.

• Drowsiness: The tendency to sleep.
• Dizziness: Unsteadiness or mild disorientation.
• Nausea: Some feel sick when taking it.
• Constipation: Inability to pass stool.
• Dry mouth: Reduces saliva and makes the mouth uncomfortable.
• Headache: From mild to severe.
• Confusion: Alters thought process and memory.
• Breathing problems: In some cases, serious risks of slowing breathing down at high doses.
• Allergic reactions: Difficulty in breathing, swelling, or rash.
• Withdrawal symptoms: Sudden stopping of the drug would result in sweating and chills, as well as body pain.

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How to Avoid Side Effects?

Oxycodone is effective for pain relief but could cause side effects due to misuse for your protection and well-being.

Tips to Minimize Side Effects

• Take as prescribed: Do not take more than prescribed.
• Drink lots of water: Prevents a dry mouth and constipation.
• Eat fiber-rich foods: Decreases constipation worries.
• Avoid alcohol and drugs: They might cause dangerous interactions.
• Take with food: It may help prevent nausea and stomach cramps.
• Do not crush the tablet: To avoid the risk of an overdose, swallow whole.
• Rest if dizzy: Close your eyes; sit down or lie down.
• Do not drive: Don’t engage in dangerous activities when feeling drowsy.
• Store away: Keep out of reach from children and others.
• Call your physician: If you recognize serious symptoms, seek help.

Medicine Interactions

Oxycodone may interact with other drugs, with the possibility of increasing side effects or lowering effectiveness.

• Sedatives: First off, sedatives create extreme sleepiness along with breathing difficulties.
• Alcohol: It raises the risk of dizziness and overdose.
• Sedative drugs: They can dangerously slow down one’s breathing.
• Muscle relaxants: Add weakness and excessive sleepiness.
• Antibiotics: Increases the duration of oxycodone’s action.
• Antifungal medicines: Increases the performance of oxycodone.
• Antidepressants: Tends to confuse or change mood unusually.
• Pain relievers (NSAIDs like ibuprofen): They all irritate the stomach.
• Anticonvulsants: Some may lessen oxycodone’s performance.
• Heart medicines: There is a great potential to lower blood pressure too much.

Conclusion

Oxycodone is a high-potency opioid analgesic utilized to treat severe pain due to injuries, surgeries, and chronic illnesses.

While effective, this medication needs to be used with caution to prevent side effects, addiction, or potentially fatal interactions. It should only be taken as per doctor’s orders, with no alcohol, and should have a secure place of storage.

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